Host and pathogen ecology drive the seasonal dynamics of a fungal disease, white-nose syndrome
Host, Pathogen, and Environmental Characteristics Predict White-Nose Syndrome Mortality in Captive Little Brown Myotis (Myotis lucifugus)
Host and pathogen ecology drive the seasonal dynamics of a fungal disease, white-nose syndrome
An app for eye disease, and planting memories in songbirds
Host Sarah Crespi talks with undergraduate student Micheal Munson from Baylor University in Waco, Texas, about a smartphone app that scans photos in the phone’s library for eye disease in kids. And Sarah talks with Todd Roberts of the University of Texas Southwestern Medical Center in Dallas, Texas, about incepting memories into zebra finches to study how they learn their songs. Using a technique called optogenetics—in which specific neurons can be controlled by pulses of light—the researchers introduced false song memories by turning on neurons in different patterns, with longer or shorter note durations than typical zebra finch songs. This week’s episode was edited by Podigy. Ads on this week’s show: MOVA Globes; KiwiCo.com Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast
Mysterious fast radio bursts and long-lasting effects of childhood cancer treatments
Host Sarah Crespi talks with Staff Writer Daniel Clery about the many, many theories surrounding fast radio bursts—extremely fast, intense radio signals from outside the galaxy—and a new telescope coming online that may help sort them out. Also this week, Sarah talks with Staff Writer Jennifer Couzin-Frankel about her story on researchers’ attempts to tackle the long-term effects of pediatric cancer treatment. The survival rate for some pediatric cancers is as high as 90%, but many survivors have a host of health problems. Jennifer’s feature is part of a special section on pediatric cancer. This week’s episode was edited by Podigy. Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: ESO/L. Calçada; Music: Jeffrey Cook]
Watch: Farah Khan, Sania Mirza on Koffee with Karan
Host Karan Johar gets Farah Khan and Sania Mirza on the couch.
Craziest Battle Damage Moments from Season 1
Hosts Justin and Erik smashed a lot of stuff in season 1. Check out the best highlights, including never-before-seen footage, and get ready because season 2 is going to be bigger and more destructive than ever before.
Game|Life - Retro Game Showdown
Host Chris Kohler and special guest Mike Mika show off their most prized possessions in an epic battle to be named the king of gaming collections.
Game|Life - Veronica Belmont and Jonathan Blow on the Future of Gaming
Hosts Chris Kohler and Peter Rubin welcome internet star Veronica Belmont and indie game designer Jonathan Blow to discuss the future of game consoles, indie game distribution, and what an Apple TV would mean for gamers and developers alike.
Host-guest interaction based supramolecular photodynamic therapy system: a promising candidate in the battle against cancer
DOI: 10.1039/D0CC02001J, Feature Article
Owing to its spatiotemporal selectivity and noninvasive nature, photodynamic therapy (PDT) has become a promising approach for the treatment of cancer. However, the non-targeting capability and the accompanying side effects...
The content of this RSS Feed (c) The Royal Society of Chemistry
Innovating Together in the Midst of COVID-19
Hosting our own hackathon was a chance to contribute to the COVID-19 response, and an opportunity to build new relationships with staff we don’t typically work with, promote the ideas of others, and encourage staff to leverage their creativity to think about problems.
Egypt fans help tidy up stadium after African Cup of Nations win over Zimbabwe
Hosts Egypt began their African Cup of nations campaign in fine style by beating Zimbabwe 1-0 at the Cairo International Stadium, but it was their fans who earned most praise in the aftermath.
France 2-0 Albania PLAYER RATINGS: Dimitri Payet the star again as Olivier Giroud goes off the boil
Host nation France made it two wins from two with two late goals to down Euro 2016 minnows Albania, Here, Sportsmail rates the performances inside the Stade Velodrome.
Hostage rescued from Iranian embassy siege thanks SAS hero
Sim Harris, 64, had been waiting for a visa at the embassy in South Kensington, West London, when six armed men stormed the site and took him and 25 others hostage.
KIIS FM edit segment after Kyle Sandilands' royal comments
Hosts Kyle and Jackie O spoke with the Duchess of Sussex's estranged brother, Thomas Markle Jr, on Monday morning.
Hostess debuts new TWINKIES cereal
Hostess wants you to have Twinkies for breakfast. The snack brand has teamed up with Post on the new product, recreating the beloved cream-filled sponge cake in cereal form.
Airbnb hosts advertise properties as 'Covid-19 retreats'
Hosts on Airbnb have been flouting the coronavirus lockdown rules by advertising their properties as 'Covid-19 retreats' on the popular rental website.
Holly Willoughby and Phillip Schofield present This Morning from Downton Abbey's Highclere Castle
Hosts Holly, 38, and Phillip, 57, presented This Morning from Downton Abbey's Highclere Castle on Thursday, where the TV series and film are shot.
Trump’s America is threatening the nuclear peace
Hostility to multilateralism means the forces that contained proliferation are dissipating
Host countries struggle to cope with Venezuela refugee crisis
Colombia seeks $1bn in funds as UN aid appeal falls well short of target
Hostess Brands CEO on coronavirus impact and the food supply chain
Andy Callahan, Hostess Brands CEO, joins "Closing Bell" to discuss the company's earnings.
Host of Child Pornography Online Bulletin Board Pleads Guilty to Transporting Child Pornography and Destruction of Records
According to his plea agreement, from approximately December 2006 through August 2008, Terry Lee Nolley, 47, and others conspired to operate “Country Lounge,” a secure web-based bulletin board dedicated to trading images of child pornography.
Airbnb launches virtual experiences you can enjoy from home
Hosts from all over the world will teach you how to bake, dance and draw
‘Saturday Night Live’: Donald Trump’s Presidency Takes Center Stage
Host Aziz Ansari touched upon the Women's Marches, racism and immigration in his monologue.
Host and Symbiont Cell Cycle Coordination Is Mediated by Symbiotic State, Nutrition, and Partner Identity in a Model Cnidarian-Dinoflagellate Symbiosis
The cell cycle is a critical component of cellular proliferation, differentiation, and response to stress, yet its role in the regulation of intracellular symbioses is not well understood. To explore host-symbiont cell cycle coordination in a marine symbiosis, we employed a model for coral-dinoflagellate associations: the tropical sea anemone Aiptasia (Exaiptasia pallida) and its native microalgal photosymbionts (Breviolum minutum and Breviolum psygmophilum). Using fluorescent labeling and spatial point-pattern image analyses to characterize cell population distributions in both partners, we developed protocols that are tailored to the three-dimensional cellular landscape of a symbiotic sea anemone tentacle. Introducing cultured symbiont cells to symbiont-free adult hosts increased overall host cell proliferation rates. The acceleration occurred predominantly in the symbiont-containing gastrodermis near clusters of symbionts but was also observed in symbiont-free epidermal tissue layers, indicating that the presence of symbionts contributes to elevated proliferation rates in the entire host during colonization. Symbiont cell cycle progression differed between cultured algae and those residing within hosts; the endosymbiotic state resulted in increased S-phase but decreased G2/M-phase symbiont populations. These phenotypes and the deceleration of cell cycle progression varied with symbiont identity and host nutritional status. These results demonstrate that host and symbiont cells have substantial and species-specific effects on the proliferation rates of their mutualistic partners. This is the first empirical evidence to support species-specific regulation of the symbiont cell cycle within a single cnidarian-dinoflagellate association; similar regulatory mechanisms likely govern interpartner coordination in other coral-algal symbioses and shape their ecophysiological responses to a changing climate. IMPORTANCE Biomass regulation is critical to the overall health of cnidarian-dinoflagellate symbioses. Despite the central role of the cell cycle in the growth and proliferation of cnidarian host cells and dinoflagellate symbionts, there are few studies that have examined the potential for host-symbiont coregulation. This study provides evidence for the acceleration of host cell proliferation when in local proximity to clusters of symbionts within cnidarian tentacles. The findings suggest that symbionts augment the cell cycle of not only their enveloping host cells but also neighboring cells in the epidermis and gastrodermis. This provides a possible mechanism for rapid colonization of cnidarian tissues. In addition, the cell cycles of symbionts differed depending on nutritional regime, symbiotic state, and species identity. The responses of cell cycle profiles to these different factors implicate a role for species-specific regulation of symbiont cell cycles within host cnidarian tissues.
Host Mucin Is Exploited by Pseudomonas aeruginosa To Provide Monosaccharides Required for a Successful Infection
One of the primary functions of the mucosal barrier, found lining epithelial cells, is to serve as a first-line of defense against microbial pathogens. The major structural components of mucus are heavily glycosylated proteins called mucins. Mucins are key components of the innate immune system as they aid in the clearance of pathogens and can decrease pathogen virulence. It has also been recently reported that individual mucins and derived glycans can attenuate the virulence of the human pathogen Pseudomonas aeruginosa. Here, we show data indicating that mucins not only play a role in host defense but that they can also be subverted by P. aeruginosa to cause disease. We found that the mucin MUL-1 and mucin-derived monosaccharides N-acetyl-galactosamine and N-acetylglucosamine are required for P. aeruginosa killing of Caenorhabditis elegans. We also found that the defective adhesion of P. aeruginosa to human lung alveolar epithelial cells, deficient in the mucin MUC1, can be reversed by the addition of individual monosaccharides. The monosaccharides identified in this study are found in a wide range of organisms where they act as host factors required for bacterial pathogenesis. While mucins in C. elegans lack sialic acid caps, which makes their monosaccharides readily available, they are capped in other species. Pathogens such as P. aeruginosa that lack sialidases may rely on enzymes from other bacteria to utilize mucin-derived monosaccharides. IMPORTANCE One of the first lines of defense present at mucosal epithelial tissues is mucus, which is a highly viscous material formed by mucin glycoproteins. Mucins serve various functions, but importantly they aid in the clearance of pathogens and debris from epithelial barriers and serve as innate immune factors. In this study, we describe a requirement of host monosaccharides, likely derived from host mucins, for the ability of Pseudomonas aeruginosa to colonize the intestine and ultimately cause death in Caenorhabditis elegans. We also demonstrate that monosaccharides alter the ability of bacteria to bind to both Caenorhabditis elegans intestinal cells and human lung alveolar epithelial cells, suggesting that there are conserved mechanisms underlying host-pathogen interactions in a range of organisms. By gaining a better understanding of pathogen-mucin interactions, we can develop better approaches to protect against pathogen infection.
Belarus, Czech Republic to host WU19 EURO in 2021 and 2022
Hosts have been picked for the Women's U19 final tournaments of 2021 and 2022 respectively.
UEFA Futsal EURO 2018 finals draw made
Hosts Slovenia have been handed a tough group with Italy and Serbia while France's debut finals match will be against holders Spain after the draw was made in Ljubljana.
HostGator Web Hosting
HostGator is an excellent web hosting service that's simple to use and offers an array of useful plans for consumers and small businesses. It's our top pick for shared web hosting and for novice webmasters in general.
Dawn of a new era
Hosting the women's final in a separate venue from the men's from now on is recognition of the giant strides the UEFA Women's Champions League has made in the past decade.
Serkan stunner sets up Istanbul victory
Hosts Istanbul have the early initiative in Group A after a stunning long-range strike from Serkan Uysal, a free-kick and a late penalty earned a 3-0 win against Ukraine's Ingulec.
Tenth UEFA Regions' Cup: final tournament draw
Hosts Istanbul must face qualifying stars Zagreb in the group stage following the draw for the tenth UEFA Regions' Cup finals, with former winners Castilla y León in the other section.
Hosting24 coupons
Offers get Hosting24 coupons 50% off at offersget.com site. 100% working offersget Hosting24 coupon codes, offers on Shared, Reseller, VPS, Dedicated server hosting.
Hosting24 hosting services? | Hosting24 Hosting company detail at offersget.com site - Basic Web Hosting is one of the least expensive and most regular kind of web hosting services accessible, and furthermore the most ideal approach to begin a website. Shared hosting allude to a web access in which single server is dispensed between numerous sites. Said beneath are the advantages and downsides of this hosting arrangement.
Hostage
Promises are made to be broken, Thwarted, Made again, Whilst Jasmine pours, Perfume; Where God, Is an impression, a Figment, Asking why, if Birds and fish and, Creatures of all kinds, Flourish, You terrorize one other? Impossible, Even at a crimson sunset, to Say sorry first, Survive polluting Earth? Picture – ♦Reuters/Daily Mail♦ -short evocative […]
Episode 56 - The Internet of Yahoo! (IoY!) Viral sensations and Marissa Mayer
Host Matt Egan leads a three pronged tech attack on the week's news with David Price and Scott Carey.
The gang discuss 'BBC Dad' and why the professor's hilarious children are the perfect example of viral video. David Price also examines the news cycle of such treats, and why ambulance drivers aren't on Twitter all the time.
With Marissa Mayer leaving Yahoo! in tatters, renamed, but with a wad of cash reportedly in her account, Scott leads the line in exploring where it went wrong and why it has been such a public fall from grace. But at age 41, surely there's another chapter in Mayer's story?
See acast.com/privacy for privacy and opt-out information.
Episode 48 - The Internet of the International Ruling Class (IotIRC) Nintendo Switch, Davos and app prices
Host Matt Egan clips us round the ear and tells us to listen up as we chat yet more tech and then some other stuff about tech.
Consumer tech editor at PC Advisor Chris Martin lays down his definitive opinion after he went hands on with the Nintendo Switch this week, and why the company really should have had their star plumber ready in time for launch.
Tamlin Magee, Online Editor at Computerworld UK then takes us through the odd goings on at Davos, and whether or not the elite can identify with what tech actually means to real working people.
To round us up, Acting Macworld UK Editor David Price explains why app prices are going up in the UK for iOS users, and why it might - might - not be UKIP's fault. Sort of.
See acast.com/privacy for privacy and opt-out information.
Episode 45 - The Internet of Social Responsibility (IoSR)
Host Henry Burrell leads the team into a tangle of nitty gritty tech topics in the penultimate pod of the year.
Macworld UK Acting Editor David Price tells us why Apple and Nintendo very nearly scored a home run with Super Mario Run, but just missed out.
The team, led by Charlotte Jee, Editor of Techworld then tackle Amazon's latest endeavour to solve first world problems (provided you live in Cambridge) (13 mins).
Tamlin Magee, Online Editor at Techworld then leads us onto the sticky topic of defining extreme terror online and which big companies have a responsibility to police the Internet (27 mins).
See acast.com/privacy for privacy and opt-out information.
Episode 40: The Internet of Trump Sadness (IoTS) Trump on tech, Daydream & Tesco Bank hack
Host Matt Egan is in a sombre mood this week as the tech industry comes to terms with a Donald Trump US presidency. Staff writer at Macworld UK dives into what this could mean for Silicon Valley, Apple products and wether social media is at fault.
Then producer Chris comes on to discuss the latest addition to the VR headset market with Google's Daydream. Will it be held back by a lack of applications though? (14:45)
Finally, online editor at Computerworld UK talks about the biggest data breach at a UK bank, as Tesco Bank suffers a £2.5 million cyber theft and what this means for the banking industry as a whole (25:00).
See acast.com/privacy for privacy and opt-out information.
Episode 27 - The Internet of No Man's Sky (IoNMS) NMS hype, open banking and emojis
Host Matt Egan is joined by the world's number one authority on No Man's Sky, producer Chris, to discuss the hype around the vast Playstation and PC game, how it was made and parallel universes.
Scott Carey, online editor at Techworld.com jumps in to speak about the government's Open Banking report and how technology could change the way we bank in the future (16:00).
Finally, acting editor at Macworld UK David Price is talking water pistol emojis and the strange politics of Apple (27:00).
See acast.com/privacy for privacy and opt-out information.
Episode 25 - The Internet of Bread (IoB) Windows 10, Verizon buys Yahoo! & Apple results
Hosting duties fall to Henry Burrell this week as he discusses the deadline for the free Microsoft Windows 10 update with Chris Minasians, staff writer at PC Advisor.
Scott Carey, online editor at Techworld.com jumps in to talk about why the Verizon deal for Yahoo is ridiculous and charts the missteps that got the company to this point (15:00).
Finally, regular guest David Price discusses Apple's less than stellar financial results and if the iPhone is plateauing (26:00).
See acast.com/privacy for privacy and opt-out information.
Episode 19 - The Internet of Xbox 'Hank' Scorpio (IoXHS) LinkedIn, Xbox vs Playstation & WWDC news
Host Matt Egan is joined by Online Editor at Techworld.com Scott Carey to break down Microsoft's mega acquisition of LinkedIn.
Staff Writer at PC Advisor Chris joins in to discuss all of the news coming out of E3 and how Xbox and Playstation are set to battle it out again this summer, or will Nintendo and Zelda steal the show? (13:00).
Finally, David Price comes on to talk about all of the news coming out of Apple's WWDC developer conference this week, from Hair Force One to watchOS, tvOS, macOS and iOS (26:30)
And please do share, rate and review the UK Tech Weekly Podcast.
See acast.com/privacy for privacy and opt-out information.
Episode 18 - The Internet of the EU (IoEU) Website crashes, Oculus games & WWDC
Host Matt Egan is joined this week by Henry Burrell, staff writer at Macworld UK to talk about the EU referendum website crashing
Lewis Painter, staff writer at PC Advisor, jumps in to chat about Oculus Rift games and how immersive they are.
Finally regular David Price comes on to talk about Apple's upcoming WWDC software developer conference and what we can (and cannot) expect.
See acast.com/privacy for privacy and opt-out information.
Episode 15 - The Internet of ill Advised Man Buns (IoIAMB) Google I/O and terrible film adaptations
Host Matt Egan is joined by producer Chris to talk about the raft of announcements coming out of the Google I/O developer conference this week, including Android N, Google assistant and Allo.
Techworld.com editor Charlotte Jee joins in to discuss driverless cars (17:00) following the Queen's speech this week.
Finally, acting editor at Macworld.co.uk David Price talks about terrible film adaptations of video games, from Angry Birds to World of Warcraft (29:00).
Don't forget to like, share and tell your friends!
See acast.com/privacy for privacy and opt-out information.
